{"id":111,"date":"2024-03-19T18:36:51","date_gmt":"2024-03-19T18:36:51","guid":{"rendered":"https:\/\/terviseleht.eu\/?p=111"},"modified":"2024-03-19T18:36:51","modified_gmt":"2024-03-19T18:36:51","slug":"uus-tohus-meetod-kopsuhaiguste-raviks","status":"publish","type":"post","link":"https:\/\/terviseleht.eu\/?p=111","title":{"rendered":"Uus t\u00f5hus meetod kopsuhaiguste raviks"},"content":{"rendered":"\n

Meetod avab uksed n\u00e4iteks ts\u00fcstilise fibroosi jt seni kehvasti ravitavate kopsuhaiguste raviks.<\/h4>\n\n\n\n

Penn Engineers on v\u00e4ljat\u00f6\u00f6tanud uue vahendi kopsude ravimiseks. Seda tehakse lipiidsete nanoosakeste (#LNP<\/a>) ehk v\u00e4iksete kapslite abil, mida #Moderna<\/a> ja #Pfizer<\/a>-BioNTech kasutasid #COVID<\/a>-19 vaktsiinides mRNA kohaletoimetamiseks. See avab uksed n\u00e4iteks ts\u00fcstilise fibroosi jt seni kehvasti ravitavate kopsuhaiguste uudsetele raviv\u00f5imalustele.<\/p>\n\n\n\n

Dotsent Michael J. Mitchell tutvustab ajakirjas #Nature<\/a> Communications avaldatud artiklis uut meetodit, mille abil saab t\u00f5husalt m\u00e4\u00e4rata, millised LNP-d seostuvad t\u00f5en\u00e4oliselt kopsude ja mitte maksaga. Mitchell \u00fctleb: “Maks on nii kujundatud, et LNP-d kipuvad filtreeruma maksarakkudes ja neil on raske mujale j\u00f5uda. Kopsude sihtimise v\u00f5imalus v\u00f5ib muuta kopsuv\u00e4hi v\u00f5i ts\u00fcstilise fibroosi p\u00f5deva inimese elu.\u201c<\/p>\n\n\n\n

P\u00e4rast LNP tuvastamist, mis tungis edukalt just kopsurakkudesse, andsid teadlased seda molekuli kopsuv\u00e4higa hiirtele. Ravil oli selgelt v\u00e4ljendunud positiivne m\u00f5ju – kasvaja suurus v\u00e4henes drastiliselt. Selle p\u00f5hjuseks oli, et kopsurakkudesse edastati mRNA ja gRNA ahelad, mis p\u00e4rsivad kopsukasvajate kasvu.<\/p>\n\n\n\n

V\u00e4ljat\u00f6\u00f6tatud meetod on kiire, odav ja t\u00f5hus.<\/strong><\/p>\n\n\n\n

Illustratsioon: Mitchelli Lab Allikas: https:\/\/www.nature.com\/articles\/s41467-024-45422-9<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Meetod avab uksed n\u00e4iteks ts\u00fcstilise fibroosi jt seni kehvasti ravitavate kopsuhaiguste raviks. Penn Engineers on v\u00e4ljat\u00f6\u00f6tanud uue vahendi kopsude ravimiseks. Seda tehakse lipiidsete nanoosakeste (#LNP) ehk v\u00e4iksete kapslite abil, mida… <\/p>\n","protected":false},"author":2,"featured_media":112,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[7],"tags":[67,110,111,109],"class_list":["post-111","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ravi-ja-ravimid","tag-kopsud","tag-kopsuhaigused","tag-kopsuvahk","tag-tsustiline-fibroos"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t