{"id":252,"date":"2024-04-29T11:49:48","date_gmt":"2024-04-29T11:49:48","guid":{"rendered":"https:\/\/terviseleht.eu\/?p=252"},"modified":"2024-04-29T11:49:48","modified_gmt":"2024-04-29T11:49:48","slug":"kaalu-langetav-rasv-ehk-miks-eakal-on-kulm-ja-lapsel-palav%e2%9d%93","status":"publish","type":"post","link":"https:\/\/terviseleht.eu\/?p=252","title":{"rendered":"Kaalu langetav rasv ehk miks eakal on k\u00fclm ja lapsel palav\u2753"},"content":{"rendered":"\n

\u2763\ufe0f Vastus peitub tervisliku pruuni rasva aktiivsuses. Teadlased on teinud l\u00e4bimurde ja avastanud pruuni rasva aktiivsuse v\u00e4ljal\u00fclitaja ning taas sissel\u00fclitamise v\u00f5imaluse.<\/h4>\n\n\n\n

Pruun rasv ehk pruun rasvkude on teatud t\u00fc\u00fcpi rasv meie kehas, mis erineb meile paremini tuttavast valgest rasvast. Viimane teeb meile muret, kui see koguneb liig suurel hulgal n\u00e4iteks k\u00f5hu piirkonda. <\/p>\n\n\n\n

\ud83d\udc41\ufe0f Pruunil rasval on eriline \u00fclesanne<\/h3>\n\n\n\n

Pruun rasv aitab muuta toidust saadud energia soojuseks. Pikka aega arvasid teadlased, et pruun rasv on aktiivne vaid vasts\u00fcndinutel ja veidi ka varases nooruses. See seletab osaliselt, miks vasts\u00fcndinud ja lapsed saavad k\u00fclmaga reeglina paremini hakkama kui eakamad. N\u00fc\u00fcdseks on aga teada, et suhteliselt v\u00e4ikesel osal t\u00e4iskasvanutest – 5 kuni 10 protsendil – s\u00e4ilib pruuni rasvkoe k\u00f5rge aktiivsus ka suhteliselt eakana v\u00f5i kogu elu jooksul.\u00a0<\/p>\n\n\n\n

Lisaks soojatootmisele t\u00e4hendab pruuni rasva aktiivsus ka seda, et liigne kehakaal nii lihtsalt ei teki. Kuna pruun rasv p\u00f5letab kaloreid nii h\u00e4sti, p\u00fc\u00fcavad teadlased leida viise selle ohutuks aktiveerimiseks kaalulangetamiseks, kasutades ravimeid, mis suurendavad selle soojuse tootmise v\u00f5imet.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u2744\ufe0f K\u00fclm v\u00f5ib kaalulangetamise sisse l\u00fclitada<\/h3>\n\n\n\n

Kuigi pruuni rasva hulk inimeste vananedes v\u00e4heneb, v\u00f5ib see siiski aktiveeruda, n\u00e4iteks kokkupuutel k\u00fclmaga. Kui see aktiveerub, kiirendab see nende inimeste ainevahetuse kiirust, mis taas v\u00f5ib aidata stabiliseerida kaalu tingimustes, kus kalorite tarbimine on (liiga) k\u00f5rge.<\/p>\n\n\n\n

Prof Jan-Wilhelm Kornfeldi L\u00f5una-Taani \u00fclikoolist\/Novo Nordiski rasvarakkude uurimiskeskusest Adiposign ja Dagmar Wachteni Bonni \u00fclikoolihaiglast l\u00e4biviidud uuring n\u00e4itas, et pruuni rasv rakkudessel on sisseehitatud varem tundmatu mehhanism, mis selle v\u00e4lja l\u00fclitab. See piirab pruuni rasva rasvumisevastast t\u00f6\u00f6d. Uuringu \u00fcks autoritest Hande Topeli s\u00f5nul on meeskond n\u00fc\u00fcd avastanud valgu, mis vastutab selle v\u00e4ljal\u00fclitusprotsessi eest. Seda nimetatakse “AC3-AT”.<\/p>\n\n\n\n

\ud83d\udee0\ufe0f V\u00e4ljal\u00fclitaja v\u00e4ljal\u00fclitamine ravimitega<\/h3>\n\n\n\n

“Tulevikku vaadates arvame, et AC3-AT blokeerimise viiside leidmine v\u00f5ib olla paljut\u00f5otav strateegia pruuni rasva ohutuks aktiveerimiseks ning rasvumise ja sellega seotud terviseprobleemide lahendamiseks,” \u00fctleb Hande Topel. Ta selgitab, et hiired, kellel geneetiliselt AC3-AT puudus, olid rasvumise eest kaitstud osaliselt seet\u00f5ttu, et nende keha oli parem kalorip\u00f5letaja. Kuna see valk esineb ka inimesel, siis on lootust, et leitakse uus kaalulangetamise v\u00f5imalus ka inimeste jaoks.\u00a0<\/p>\n\n\n\n

Publication:<\/strong>\u00a0Sajjad Khani, Hande Topel, Ronja Kardinal et al; Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function; Nature Metabolism;
DOI:\u00a010.1038\/s42255-024-01033-8<\/a>;\u00a0https:\/\/www.nature.com\/articles\/s42255-024-01033-8<\/a><\/p>\n\n\n\n

Loe ka Milline hommikus\u00f6\u00f6k saledab ja parandab keskendumisv\u00f5imet? https:\/\/terviseleht.eu\/?p=11<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\u2763\ufe0f Vastus peitub tervisliku pruuni rasva aktiivsuses. Teadlased on teinud l\u00e4bimurde ja avastanud pruuni rasva aktiivsuse v\u00e4ljal\u00fclitaja ning taas sissel\u00fclitamise v\u00f5imaluse. Pruun rasv ehk pruun rasvkude on teatud t\u00fc\u00fcpi rasv… <\/p>\n","protected":false},"author":2,"featured_media":254,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[9,10,7,11],"tags":[212,214,213,18,208,104,141,21,210,209,211,20,17],"class_list":["post-252","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ennetus","category-liikumisroom-ja-trenn","category-ravi-ja-ravimid","category-toit-ja-toidulisandid","tag-energia","tag-kaalulangus","tag-kalorid","tag-kehakaal","tag-kulm","tag-mehed","tag-mikrobioom","tag-naised","tag-pruun","tag-rasv","tag-rasvkude","tag-rasvumine","tag-toit"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/posts\/252"}],"collection":[{"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=252"}],"version-history":[{"count":1,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/posts\/252\/revisions"}],"predecessor-version":[{"id":255,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/posts\/252\/revisions\/255"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=\/wp\/v2\/media\/254"}],"wp:attachment":[{"href":"https:\/\/terviseleht.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=252"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=252"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/terviseleht.eu\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=252"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}